Friday April 20, Krakow

Friday April 20, Krakow

00.01 - 23.59
WCO-IOF-ESCEO
08.00
Opening of the commercial exhibition
08.00 - 09.00
NON-SPONSORED SYMPOSIA
Meeting Room 1
Breast Cancer and Bone Health– Joint session of the Cancer And Bone Society (CABS) and the IOF
Chairpersons: Jean‑Jacques Body, Peyman Hadji
Adjuvant antiresoptive treatment in women with breast cancer - Cancer Treatment Induced Bone Loss (CTIBL) and much more Peyman Hadji
Treatment of metastatic bone disease in women with breast cancer - New insights of an old story Jean‑Jacques Body
Meeting Room 2
Sarcopenia: Problem-solving a new lifestyle disease
Chairperson: Kerrie  Sanders
Reducing the burden of sarcopenia: A healthy lifestyle throughout the lifetime David Scott
Is the risk of sarcopenia socially patterned? Sharon L. Brennan‑Olsen
Sarcopenia: is the right food the key to prevention? Sandra Iuliano‑Burns
International dialogue and problem-solving
Meeting Room 3
Bone fragility in diabetes
Chairperson: Serge Ferrari
Pathophysiology of bone fragility in diabetes Serge Ferrari
Fracture risk assessment in diabetes Emmanuel Biver
Osteoporosis drug effects in diabetics Nicola Napoli
Meeting Room 4
Treating Osteosarcopenia by Targeting Muscle and Bone: Actuality and Perspectives
Chairperson: Gustavo Duque
Combined effects of vitamin D on muscle and bone: a review of evidence among senior adults age 65+ Heike A. Bischoff‑Ferrari
Novel Exercise and Nutritional Approaches to Optimize Bone, Muscle and Mobility into Old Age Robin Daly
Pharmacological Treatment of Osteosarcopenia: How to target bone and muscle at the same time? Gustavo Duque
Meeting Room 5
Global Map of Dietary Calcium Intake reveals large geographic regions of low intake – a call to action
Chairperson: Bess Dawson‑Hughes
Introduction Bess Dawson‑Hughes
Calcium intake and its implications in India Ambrish Mithal
Calcium intake and its implications in China and the Pacific Rim Wei‑bo Xia
Discussion
08.00 - 09.00
ESCEO-WHO SYMPOSIA
Meeting Room 6
Principles for the engagement of patients in the preparation of clinical and regulatory guidelines : outcomes of an experts consensus meeting organized by the World Health Organization and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases.
Chairpersons: Famida Jiwa, Peter Tugwell
08.00 ‣ Welcome and scope of the problem Peter Tugwell
08.05 ‣ A journey in patient partnership John Kirwan
08.15 ‣ Principles for patients engagement in the preparation of clinical guidelines Maarten de Wit
08.30 ‣ Principles for patients engagement in the preparation of regulatory guideline Nathalie Bere
08.45 ‣ Discussion - Leaders Philip Conaghan, Daniel Pinto
09.00 ‣ Conclusion Famida Jiwa
Panel: Isabelle Aujoulat, Nathalie Bere, Maria Luisa Brandi, Olivier Bruyère, Philip Conaghan, Cyrus Cooper, Maarten de Wit, Philippe Halbout, Mickaël Hiligsmann, Famida Jiwa, John A. Kanis, John Kirwan, Andrea Laslop, Daniel Pinto, Jean‑Yves Reginster, René Rizzoli, Marieke Scholte, Peter Tugwell, Lia Van der Ham, Mila Vlaskovska
Meeting Room 7
Assessment of Physical Performance in daily clinical practice: Outcomes of an Experts’ consensus meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) under the auspices of the World Health Organization
Chairpersons: Islene Araujo de Carvalho, Roger A. Fielding
08.00 ‣ Welcome Cyrus Cooper
08.05 ‣ Scope of the problem René Rizzoli
08.10 ‣ Principles for the standardization of the assessment of physical performance Alfonso Cruz Jentoft
08.25 ‣ Principles for the standardization of the assessment of muscle strength and power Laura Schaap
08.40 ‣ Discussion - Leader: Ivan Bautmans
08.55 ‣ Conclusion Stefania Maggi
Panel: Islene Araujo de Carvalho, Jürgen Bauer, Ivan Bautmans, Roberto Bernabei, Olivier Bruyère, Cyrus Cooper, Alfonso Cruz Jentoft, Bess Dawson‑Hughes, Roger A. Fielding, Jean‑Marc Kaufman, Stefania Maggi, Jean Petermans, Jean‑Yves Reginster, René Rizzoli, Yves Rolland, Laura Schaap, Daniel Uebelhart
09.00 - 12.10
Auditorium A
SCIENTIFIC SESSION I
Chairpersons: John A. Kanis, Jean‑Yves Reginster
09.00
Auditorium A
Plenary Lecture 1
Frax : 10 years later Cyrus Cooper
09.30
Auditorium A
Oral communications selected from abstracts
09.30
Auditorium A
OC1
‣ ABALOPARATIDE FOR RISK REDUCTION OF NONVERTEBRAL AND VERTEBRAL FRACTURES IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS: AN UPDATED NETWORK META-ANALYSIS
Presenting author: J.‑Y. Reginster
Authors: F. Bianic, R. Campbell, M. Martin, S. A. Williams, L. A. Fitzpatrick
09.40
Auditorium A
OC2
‣ PERSISTENT FRACTURE RISK REDUCTION WITH ABALOPARATIDE-SC FOLLOWED BY 24 MONTHS OF ALENDRONATE
Presenting author: S. Papapoulos
Authors: H. G. Bone, L. A. Fitzpatrick, B. Mitlak, M.‑Y. Hu, G. Hattersley, K. G. Saag, R. Rizzoli
09.50
Auditorium A
OC3
‣ COST-EFFECTIVENESS OF ABALOPARATIDE FOR THE TREATMENT OF POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS
Presenting author: M. Hiligsmann
Authors: S. A. Williams, L. A. Fitzpatrick, J.‑Y. Reginster
10.00
Auditorium A
OC4
‣ RESULTS FROM A 52-WEEK, PHASE 2A STUDY OF AN INTRA-ARTICULAR, WNT PATHWAY INHIBITOR, SM04690, FOR KNEE OSTEOARTHRITIS
Presenting author: J. Tambiah
Authors: N. Lane, Y. Yazici, T. McAlindon, A. Gibofsky, D. Clauw, C. Swearingen, A. Difrancesco, M. Hochberg
10.10
Auditorium A
OC5
‣ JOINT SPACE WIDTH CRITERIA CAN REDUCE KNEE OA TRIAL HETEROGENEITY: PHASE 2 POST-HOC DATA FROM WNT PATHWAY INHIBITOR, SM04690
Presenting author: P. Conaghan
Authors: J. Tambiah, C. Swearingen, S. Kennedy, M. Bowes, A. Brett, C. Lattermann
10.20
Auditorium A
Presentation of the ESCEO-AgNovos Healthcare Young Investigator Awards
Jean‑Yves Reginster
10.30
Auditorium A
Plenary Lecture 2
Bone microstructure and fracture risk: implications for the clinician? Serge Ferrari
11.00
Auditorium A
Oral Communications selected from abstracts
11.00
Auditorium A
OC6
‣ SYSTEMATIC SCREENING USING FRAX LEADS TO INCREASED USE OF, AND ADHERENCE TO, ANTI-OSTEOPOROSIS MEDICATIONS: THE UK SCOOP TRIAL
Presenting author: C. Parsons
Authors: N. C. Harvey, L. Shepstone, J. A. Kanis, E. Lenaghan, S. Clarke, R. Fordham, N. Gittoes, I. Harvey, R. Holland, A. Heawood, N. M. Redmond, A. Howe, T. Marshall, T. J. Peters, D. Torgerson, T. W. O'Neill, E. V. McCloskey, C. Cooper
11.10
Auditorium A
OC7
‣ LOCAL OSTEO-ENHANCEMENT PROCEDURE UTILIZING A NOVEL TRIPHASIC CALCIUM BASED IMPLANT INCREASES LONG TERM FEA-ESTIMATED PROXIMAL FEMUR STRENGTH IN OSTEOPOROTIC WOMEN
Presenting author: M. Bouxsein
Authors: T.  Keaveny, D. Lee, J. Stroncek, R. Hill, J. Howe, B. Huber
11.20
Auditorium A
OC8
‣ A META-ANALYSIS OF 4 CLINICAL TRIALS OF DENOSUMAB (DMAB) COMPARED WITH BISPHOSPHONATES (BPS) IN POSTMENOPAUSAL WOMEN PREVIOUSLY TREATED WITH ORAL BISPHOSPHONATES (OBPS)
Presenting author: J. Malouf
Authors: P. D. Miller, N. Pannacciulli, A. Singer, E. Czerwinski, H. G. Bone, C. Wang, R. B. Wagman, J. P. Brown
11.30
Auditorium A
OC9
‣ TEN-YEAR CONTINUED NONVERTEBRAL FRACTURE (NVFX) REDUCTION IN POSTMENOPAUSAL OSTEOPOROSIS WITH DENOSUMAB (DMAB) TREATMENT
Presenting author: S. Ferrari
Authors: P. W. Butler, D. L. Kendler, P. D. Miller, C. Roux, A. T. Wang, R. B. Wagman, E. M. Lewiecki
11.40
Auditorium A
OC10
‣ DENOSUMAB IMPROVES GLYCEMIC CONTROL OF TYPE 2 DIABETIC PATIENTS WITH OSTEOPOROSIS
Presenting author: C.K. Chew
Authors: S. Khosla, R. Rizza, J. Geske, B. Clarke
11.50
Auditorium A
OC11
‣ EVALUATION OF INVASIVE ORAL PROCEDURES AND EVENTS (OPES) IN WOMEN WITH POSTMENOPAUSAL OSTEOPOROSIS (PMO) TREATED FOR UP TO 10 YEARS WITH DENOSUMAB (DMAB): RESULTS FROM THE PHASE 3 FREEDOM OPEN-LABEL EXTENSION (EXT)
Presenting author: P. W. Butler
Authors: N. B. Watts, J.T. Grbic, N. Binkley, X. Yin, A. Tierney, R. B. Wagman, M. R. McClung
12.00
Auditorium A
OC12
‣ EFFECTS OF ROMOSOZUMAB IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS AFTER 2 AND 12 MONTHS ASSESSED BY MICRO COMPUTED TOMOGRAPHY AND HISTOMORPHOMETRY ON ILIAC CREST BONE BIOPSIES
Presenting author: P. Chavassieux
Authors: R. D. Chapurlat, J.‑P. Roux, N. Portero‑Muzy, P. Garcia, J. P. Brown, S. Horlait, C. Libanati, R. Boyce, A. Wang, A. Grauer
14.00 - 15.00
MEET-THE-EXPERT SESSIONS
Meeting Room 4
Local bone treatment in osteoporosis
Andreas Kurth
Meeting Room 1
Bone fragility in young people: when and how to investigate ?
Serge Ferrari
Meeting Room 2
Hypophosphatasia, diagnosis and management
Maria Luisa Brandi
Meeting Room 3
Muscle function assessment in daily practice
Olivier Bruyère, Charlotte Beaudart
14.00 - 15.00
Poster Area
Poster Viewing Session I
14.00 - 15.17
Podium
Oral presentation of selected posters
Chairperson: Fanny Buckinx
14.00
Podium
P656
‣ SERUM CTX PREDICTS HIP FRACTURE RISK INDEPENDENTLY OF FRAX (WITHOUT BMD) BUT NOT OF BMD – A POST HOC ANALYSIS FROM THE SHEFFIELD HIP FRACTURE STUDY
Presenting author: E. V. McCloskey
Authors: H. Johansson, A. Oden, N. C. Harvey, R. Eastell, F. Gossiel, J. A. Kanis
14.07
Podium
P153
‣ DIETARY PROTEIN INTAKE ABOVE THE CURRENT RDA AND BONE HEALTH: A SYSTEMATIC REVIEW AND META-ANALYSIS
Presenting author: T. C. Wallace
Author: C. L. Frankenfeld
14.14
Podium
P188
‣ INCREASED MORTALITY RISK IN MEN WITH HIGH DIETARY CALCIUM INTAKE BUT NOT IN WOMEN
Presenting author: A. J. Rodriguez
Authors: D. Scott, B.  Khan, A. Hodge, D. R. English, G. G. Giles, B. Abrahamsen, P. R. Ebeling
14.21
Podium
P701
‣ ASSOCIATIONS BETWEEN RADIUS LOW-FREQUENCY AXIAL ULTRASOUND VELOCITY AND BONE FRAGILITY IN ELDERLY MEN AND WOMEN
Presenting author: E. Biver
Authors: J. Pepe, A. De Sire, T. Chevalley, S. Ferrari
14.28
Podium
P510
‣ VITAMIN D STATUS IN ADOLESCENCE IS AN INDEPENDENT PREDICTOR OF BONE MINERAL DENSITY AND MICROARCHITECTURE IN EARLY ADULTHOOD: A 17-YR PROSPECTIVE COHORT STUDY
Presenting author: Y. Yang
Authors: F. Wu, T. Winzenberg, G. Jones
14.35
Podium
P308
‣ BUROSUMAB, AN ANTI-FGF23 MONOCLONAL ANTIBODY, FOR X-LINKED HYPOPHOSPHATEMIA (XLH): ANALYSIS BY AGE FROM TWO PHASE 2 PEDIATRIC TRIALS
Presenting author: R. Padidela
Authors: T. O. Carpenter, E. A. Imel, A. A. Portale, A. Linglart, W. Högler, A. Boot, W. van't Hoff, G. S. Gottesman, M. Mao, A. Skrinar, J. San Martin, M. P. Whyte
14.42
Podium
P1065
‣ INTERVENTION THRESHOLD BASED ON FRAX AND BMD
Presenting author: H. Johansson
Authors: F. Azizieh, N. Al Ali, A. Thamer, N. C. Harvey, E. V. McCloskey, J. Kanis
14.49
Podium
P195
‣ IMPACT OF BISPHOSPHONATES IN AGE-RELATED MACULAR DEGENERATION: RETROSPECTIVE COHORT AND NESTED CASE-CONTROL STUDY
Presenting author: C. Garriga
Authors: M. Pazianas, S. Hawley, A. Delmestri, D. Prieto‑Alhambra, C. Cooper, A. Judge
14.56
Podium
P473
‣ POCOSTEO: POC IN-OFFICE DEVICE FOR IDENTIFYING INDIVIDUALS AT HIGH RISK OF OSTEOPOROSIS AND OSTEOPOROTIC FRACTURE
Presenting author: P. Khashayar
Authors: F. Leys, P. Lopes, A. Ostovar, G. Schols, R. Gransee, D. Latta, P. Biggs, I. J. Riley, C. K. O'Sullivan, I. Katakis, M. Ortiz, J. L. L. Acero, R. Hoogenboom, F. Devlieghere, P. Ragaert, B. Barredo, M. Adriaens, B. Obermayer‑Pietsch, H. P. Dimai, B. Larijani, J. Vanfleteren
15.03
Podium
P524
‣ ANTI-OSTEOPOROSIS MEDICATION PRESCRIPTIONS AND INCIDENCE OF SECONDARY FRACTURE AMONGST HIP FRACTURE PATIENTS IN ENGLAND AND WALES: AN AGE STRATIFIED INTERRUPTED TIME SERIES ANALYSIS
Presenting author: S. Hawley
Authors: D. Prieto‑Alhambra, A. Delmestri, N. K. Arden, C. Cooper, A. Judge, M. K. Javaid
15.10
Podium
P443
‣ FRAME STUDY: THE FOUNDATION EFFECT OF REBUILDING BONE WITH ONE YEAR OF ROMOSOZUMAB LEADS TO CONTINUED LOWER FRACTURE RISK AFTER TRANSITION TO DENOSUMAB
Presenting author: S. Ferrari
Authors: F. Cosman, D. B. Crittenden, A. Khan, N. E. Lane, K. Lippuner, T. Matsumoto, C. E. Milmont, C. Libanati, A. Grauer
14.00 - 15.00
Meeting Room 6
IOF-ESCEO SYMPOSIUM
Meeting Room 6
Nutrition and physical activity in the prevention and treatment of sarcopenia: Outcomes of the IOF-ESCEO sarcopenia Working Groups
Chairpersons: Charlotte Beaudart, Elaine M. Dennison
14.00 ‣ Welcome and scope of the problem Nicholas Harvey
14.05 ‣ Methodology of the systematic review Elaine M. Dennison
14.15 ‣ Outcomes of the systematic review Charlotte Beaudart
14.25 ‣ Dairy products in the prevention and treatment of sarcopenia: Outcomes of the ESCEO Working Groups Jean‑Yves Reginster
14.40 ‣ Discussion - Leader: Roland D. Chapurlat
14.55 ‣ Conclusion Charlotte Beaudart

This Symposium was made possible through an Unrestricted Educational Grant from the “European Milk Forum” (EMF) and the “Centre de recherche et d’information nutritionnelles” (CERIN)

15.00 - 16.45
Meeting Room 6
COMMITTEE OF NATIONAL SOCIETIES SPECIAL PLENARY SESSION
‣ Clinical, social, ethical and economic burden of osteoporosis and fragility fractures
Chairperson: Jean‑Yves Reginster
15.03
Meeting Room 6
OCs1
‣ ONE YEAR OUTCOMES OF FRACTURE LIAISON SERVICE AT THE NATIONAL TAIWAN UNIVERSITY HEALTHCARE SYSTEM
Presenting author: D.‑C. Chan
Authors: R.‑S. Yang, C.‑H. Hong, K.‑S. Tsai
15.11
Meeting Room 6
OCs2
‣ RELATIONSHIPS OF PLASMA TOTAL HOMOCYSTEINE, FOLATE AND VITAMIN B12 LEVELS TO VERTEBRAL FRACTURE AND BONE MINERAL DENSITY IN MOROCCAN HEALTHY POSTMENOPAUSAL WOMEN
Presenting author: A. El Maataoui
Authors: S. Nadifi, A. El Maghraoui, Z. Ouzzif
15.19
Meeting Room 6
OCs3
‣ SARCOPENIA AND QUALITY OF LIFE QUESTIONNAIRE (SARQOL®): GREEK CROSS CULTURAL ADAPTATION
Presenting author: C. Matzaroglou
Authors: M. Tsekoura, E. Billis, J. Gliatis, E. Tsepis, G.K. Sakkas, C. Beaudart, O. Bruyère, E. Panagiotopoulos
15.27
Meeting Room 6
OCs4
‣ FRAILTY AND RISK OF FRAGILITY FRACTURES IN PARTICIPANTS WITH TYPE 2 DIABETES MELLITUS
Presenting author: G. Li
Authors: J. Prior, A. Papaioannou, L. Thabane, M. Levine, J. Adachi
15.35
Meeting Room 6
OCs5
‣ DIETARY CALCIUM INTAKE IN CAUCASIAN AND EAST ASIAN ADOLESCENTS: A STUDY OF EXPATRIATE MALE HIGH SCHOOLERS AGED 16-18 YEARS RESIDING IN SINGAPORE
Presenting author: M. Chandran
Author: A.D. Chandran
15.43
Meeting Room 6
OCs6
‣ THE ORGANIZATION OF SECONDARY FRACTURE PREVENTION SERVICES IN RUSSIAN FEDERATION
Presenting author: O.  Lesnyak
Authors: K. Belova, O. Ershova
15.51
Meeting Room 6
OCs7
‣ ASSOCIATION BETWEEN OSTEOPOROSIS AND COGNITIVE IMPAIRMENT IN A COMMUNITY DWELLING OLDER POPULATION
Presenting author: F. Sharifi
Authors: G. Shafiee, R. Heshmat, I. Nabipour, B. Larijani, A. Ostovar
15.59
Meeting Room 6
OCs8
‣ VERTEBRAL FRACTURES CASCADE: POTENTIAL ETIOLOGIES AND RISK
Presenting author: H. Che
Authors: V. Breuil, B. Cortet, J. Paccou, L. Chapuis, F. Debiais, R. M. Javier, N. Mehsen Cetre, T. Thomas, C. Roux, K. Briot, S. Loiseau Peres
16.07
Meeting Room 6
OCs9
‣ PREVALENCE OF OSTEOPOROSIS IN THE TURKISH WOMEN, RISK FACTORS AND THEIR AWARENESS ABOUT OSTEOPOROSIS ACCORDING TO THE CAMPAIGN OF “HEALTHY BONES & STRONG WOMEN”
Presenting author: Y. Kirazli
Authors: F.C. Atamaz Calis, S. Tuzun, O. El, O. Peker, B. Durmaz, S. Oncel
16.15
Meeting Room 6
OCs10
‣ TRABECULAR BONE SCORE OF CHILDREN AND ADOLESCENTS 4 TO 19 YEARS OLD IN MEXICO CITY
Presenting author: M. A. Guagnelli
Authors: R. Ambrosi, D. Lopez‑Gonzalez, R. Winzenrieth, L. Del Rio, P. Clark
16.23
Meeting Room 6
OCs11
‣ CROSS CULTURAL ADAPTATION OF THE SARQOL QUESTIONNAIRE INTO HUNGARIAN LANGUAGE
Presenting author: A. I. Gasparik
Author: L. Hodinka
16.35
Meeting Room 6
Presentation of the IOF Committee of National Societies Medal
Jean‑Yves Reginster
15.00 - 17.00
Auditorium A
SCIENTIFIC SESSION II
Chairpersons: Cyrus Cooper, Olivier Bruyère
15.00
Auditorium A
Plenary Lecture 3
New perspectives in osteoarthritis management Philip Conaghan
15.30
Auditorium A
Presentation of the IOF President's Award
Cyrus Cooper
15.35
Auditorium A
Presentation of the ESCEO-IBSA Best Oral Presentation Award
Olivier Bruyère
15.35
Auditorium A
Presentation of the ESCEO-IBSA Young Investigator Award
Cyrus Cooper
15.40
Auditorium A
Oral communications selected from abstracts
15.40
Auditorium A
OC13
‣ A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY INVESTIGATING THE EFFICACY AND SAFETY OF BUROSUMAB, AN ANTI-FGF23 ANTIBODY, IN ADULT X-LINKED HYPOPHOSPHATEMIA (XLH)
Presenting author: P. Kamenicky
Authors: R. Lachmann, T. O. Carpenter, M. Cohen‑Solal, R. Eastell, M. L. Brandi, R.K. Crowley, S.H. Ralston, K. Javaid, R. Keen, K. Briot, H. I. Cheong, Y. Imanishi, N. Ito, H. Tanaka, J. Zhang, C. Theodore‑Oklota, M. Mealiffe, J. San Martin, K. Insogna
15.50
Auditorium A
OC14
‣ EFFECTS OF RESISTANCE AND IMPACT EXERCISE TRAINING ON TRABECULAR BONE MICROARCHITECTURE AND KNEE CARTILAGE HEALTH IN OLDER ADULTS: AN 18-MONTH RANDOMIZED CONTROLLED TRIAL
Presenting author: R.M. Daly
Authors: J. Gianoudis, M.E. Kersh, Y. Wang, C.A. Bailey, P. R. Ebeling, C.A. Nowson, K. Sanders, F. Cicuttini, K.D. Hill
16.10
Auditorium A
OC16
‣ EFFECT OF LACTOBACILLUS REUTERI ON BONE LOSS IN OLDER WOMEN WITH LOW BONE MINERAL DENSITY – A RANDOMIZED CLINICAL TRIAL
Presenting author: M. Lorentzon
Authors: G. Nilsson, D. Sundh, F. Bäckhed
16.20
Auditorium A
OC17
‣ MORE FREQUENT AND MORE SUSTAIN OSTEOPOROSIS TREATMENT AFTER FRAGILITY VERTEBRAL FRACTURES WHEN INTRODUCED EARLY IN INPATIENTS THAN DELAYED IN OUTPATIENTS
Presenting author: T. Chevalley
Authors: H. Spechbach, I. Fabreguet, E. Saule, M. Hars, J. Stirnemann, S. Ferrari, R. Rizzoli
16.30
Auditorium A
Plenary Lecture 4
Management of iatrogenic osteoporosis Peyman Hadji